DMT Cartridges: Do They Contain Components of Ayahuasca?
While it’s also found in ayahuasca (which, in said form, lasts a few hours), drinking ayahuasca or smoking powder from a pipe isn’t the only way to experience DMT. It can also be mixed into e-liquid (a.k.a. “vape juice”) and inhaled using common vaporizers. These vapes require no alterations for those who want to use them for DMT, according to various online forums for DMT enthusiasts, who recommend using the DMT e-liquid with vapes like the SMOK AL85 (which retails for $50 USD). Pre-loaded DMT vape pens can also be found online for as little as $280 for a package of five cartridges.
And while the intensity of the experience is dose-dependent, vaping DMT can cause similarly intense hallucinations as consuming it in more traditional ways.
Di-Methyl-Tryptamine( DMT), commonly referred to as “DMT” is one of the most powerful psychoactive substances known to mankind, and interestingly is endogenously produced by the human body (along with many other forms of plant and animal life). This characteristic (biosynthesis by humans) is exceptional because it is not shared by any other psychedelic substance.
DMT is also the active hallucinogenic compound in ayahuasca, a tea brewed from the shrub Psychotria viridis used for ritual purposes by indigenous people in the Amazon. See our ayahuasca guide for more on this psychedelic brew.
People also ingest DMT in crystal form, smoking it in a pipe or bong, as well as vaporized. This form of ingestion produces a powerful but short-lasting hallucinogenic state, considered to be one of the most intense psychedelic experiences in existence.
However, while the body does naturally produce DMT (and perhaps produces it in much higher levels than previously thought), it also produces another compound called Monoamine Oxidase (MAO).
Monoamine oxidase effectively serves to nullify any psychoactive effects that perhaps would be felt due to the bodies naturally produced DMT, as it’s role in the body is to “clean” neuroreceptors by deaminating several different monoamine neurotransmitters (serotonin, dopamine, and norepinephrine are all monoamine neurotransmitters). N- N,Di-methyl-tryptamine is also a monoamine compound, so therefore is broken down by MAO before it has the chance to be transmitted through the brain from its point of synthesis in the cerebral cortex.
Although we can’t consciously feel effects from the DMT that is being created in our brains right now, when exogenous DMT (not produced by the body) is introduced in large enough amounts it is able to overcome the inhibitory action of MAO and elicit a short but very intense psychedelic experience. Another method of consumption that will allow the user to experience psychoactive effects from DMT is by mixing DMT with a Monoamine Oxidase Inhibitor (MAOI). The Ayahuasca brew, which is typically a mixture of Mimosa Hostilis root bark or Psychotria viridis (both plants which contain high levels of DMT) and the Banisteriopsis caapi vine, which is an MAOI. While these are the main ingredients in Ayahuasca, there are several other (also psychoactive) ingredients.
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